Staccato Automated System

OTRADI uses an automated robotic assay platform from Caliper Life Sciences. The setup contains a liquid handling deck, a TwisterII robotic arm, a Synergy 4 microplate reader, and an incubator. To learn more about the capabilities of our Staccato system, read below.

Liquid handling robotic workstation: Sciclone ALH3000

• This highly flexible, automated liquid handling workstation for drug discovery is configured to handle any automated, liquid-handling-application focus area including genomics, proteomics, immunoassays and cell-based assays. Designed for precision pipetting, it features a high-volume head (1-200uL) and low-volume head (nL) for liquid sampling in 24-, 48-, 96-, and 384-well microplates.

Liquid handler: Sciclone Z-8 liquid handler

• This liquid handler is designed for serial dilution, hit picking, control addition, sample transfer and other applications where there is individual and/or independently controlled access to specific single wells or groups of wells in 24-, 48-, 96- and 384-well microplates.

Microplate gripper: Sciclone ALH servo gripper

• The gripper stacks and un-stacks plates, unloads stackers and other plate-presentation devices, loads nested tips and de-lids plates.

Microplate and tip handler: HyperStak automated plate-and-tip-storage device and dispenser

• This handler stores and dispenses microplates and disposable tips for the Sciclone system.

Robotic microplate handler: Twister II microplate handler

• The heart of a completely-automated, integrated assay system, this robotic handler accesses the liquid-handling deck of the Sciclone, as well as the incubator, plate reader, and plate washer/dispenser.

Microplate washer/dispenser: BioTek 405 microplate washer/dispenser

• Dual-action manifold gives independent control of both dispense and aspirate manifolds for precise overfill washing and overflow protection in both 96- and 384-well microplates.

Barcode reader: Microscan MS-3

• Embedded compact barcode scanner for microplate database management.

Microplate incubator: Cytomat 2C incubator

• Robot-accessible, 42-microplate position incubator, featuring temperature, humidity, and gaseous atmosphere control for all automated, cell-based and non-cell-based assay systems.

Microplate reader: BioTek Synergy 4 microplate reader

• As the most advanced multidetection microplate reader, this model is designed to address the widest range of microplate-based applications. Its filter-based system is designed to allow detection of fluorescence (mercury lamp and laser), luminescence and optical density.

Software and control: Caliper iLinkPro

• Caliper Life Sciences' system integration software for assay development, method-building, assay-editing and scheduling, is used to create automated assays, track materials, manage data and run complete systems.

Training: Certified training at Caliper Training Center in Boston, Mass.

• OTRADI scientists have received certified training on the Caliper Staccato Automated System and associated software and database management at the Caliper Life Sciences headquarters.

For more information, see the Caliper LS documentation.