Otradi
Oregon Translational Research and Drug Development Institute (OTRADI)
Chembridge: DIVERSet
http://www.chembridge.com/datasheets/DIVERSet.pdf
DIVERSet™ - A "universally" diverse collection of 50,000 drug-like small molecules. The chemical library is rationally selected based on 3D pharmacophore analysis to cover the broadest part of biologically relevant pharmacophore diversity space. A highly recognized and proven primary screening tool for a wide range of both validated and new biological targets.
MicroSource Discovery: Spectrum Collection
http://msdiscovery.com/spectrum.html
The Spectrum Collection- The 2000 compounds in the SPECTRUM Collection were selected by medicinal chemists and biologists so as to provide a wide range of biological activities and structural diversity for screening programs with special emphasis on the de-novo assays emerging today. Such content provides the opportunity to evaluate drugs and biochemical tools with known biological profiles and, at the same time, explore the potential of novel structural and topographical diversity manifest in pure natural products. Each compound has a minimum of 95% purity. Approved Drug Components (50% or ~1000 compounds), Natural Products (30% or ~600 compounds), Other Bioactive Components (20% or 400 compounds).
Maybridge: HitFinder Collection
http://www.maybridge.com/portal/alias__Rainbow/lang__en/tabID__229/DesktopDefault.aspx
The 14,400 compound HitFinder collection of compounds is a subset of compounds maximized for structural diversity. The compounds are provided in microtiter plates, 1 umole each compound in dry film, 80 compounds per plate, first and last columns empty, 180 plates.
National Cancer Institute (NCI) Libraries:
Approved Oncology Drugs Set
88 compoundsDiversity Set II
1364 compoundsMechanistic Diversity Set
Compounds were chosen to represent a broad range of growth inhibition patterns in the 60 cell line screen, based on the GI50 activity of the compounds.
879 compoundsNatural Products Set
235 compounds
The Oregon Collection
The Oregon collection is made up >1000 novel, locally-sourced, natural and synthetic chemical compounds contributed by chemists and scientists from the four major Oregon research universities—Oregon State University, Portland State University, Portland Veterans Affairs Medical Center/Oregon Health and Science University, and University of Oregon. Oregon university-based researchers have provided their compounds to OTRADI's research and testing team so that they may be assayed for their drug-like ability against a number of disease targets.