OTRADI has the expertise and robotics necessary to perform high-content analysis and imaging of cellular environments in 96-well & 384-well formats. Our scientists are experts at optimization and analysis of automated cellular imaging.

We have the capabilities to:

  • Design and validate image-based cell screening assays

  • Develop and test mechanism of action (MOA) hypotheses

  • Simultaneously screen for and prioritize hits based on specificity for target and lack of cytotoxicity

  • Provide imaging and analysis of live and fixed cells

  • Identify cellular targets for drugs

  • Identify and profile enzymatic targets (kinases, proteases, phosphatases, etc.)

  • Kinetic assays to image the same cells over an extended time course

  • High-throughput analysis of fixed cells

  • Ability to analyze cell morphology and sub-cellular localization/compartmentalization

  • Assays designed for counting nuclei, cell scoring (live/dead), analyzing cell health and granularity, as well as determining mitotic index, neurite outgrowth, transfluorescence, translocation, and multi-wavelength cell scoring

Working with OTRADI

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