As we see pipelines moving to progressively complex biologics—for example, antibody drug conjugates, bispecific antibodies, fusion proteins and other antibody derivatives—the question of a well designed drug product becomes even more pertinent. Within the drug product field, pre-filled syringes and other combination products have been receiving increasing attention as the container closure system of choice for injectable drug products, where subcutaneous (SC) self-administration is preferred. As an integrated approach for Biologics product development at the interface of formulation, primary packaging…